CHOICES3: Sickle Cell Disease Parenting CHOICES
Running, not enrolling · Not applicable
Conditions studied: Sickle Cell Disease, Sickle Cell Trait
In brief
The study will use web-based data collection (SCKnowIQ) and intervention delivery strategies enhanced by nudges and tailored boosters in a sample of 430 adult men and women, aged 18-45 yr with SCD (Sickle Cell Disease) or SCT (Sickle Cell Trait), at-risk, and planning within 2 years to have a child free of SCD.
Key facts
- Study ID
- NCT05292781
- Run by
- University of Florida
- People needed
- 506
- Starts
- 2022-12-01
- Expected to finish
- 2027-06-30
- Last updated by the study team
- 2026-01-15
Who can join
Age: 18 and older, up to 45. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Diagnosis of SCD (HbSS, HbSC (Hemoglobin Sickle C Disease), HbS-beta-0 thalassemia, and HbS-beta+ thalassemia) or report of SCT (SCD is Hgb electrophoresis confirmed; SCT evaluated by SickleScan);
- Able and intends to conceive a child in the next 2 years (first child or another child);
- Speaks and reads English;
- 18 to 45 years;
- At-risk for having a child with SCD (i.e., sexual/ reproductive partner has SCD, SCT, or unknown sickle cell status); and
- Wants to avoid the risk of a child with SCD.
- The age range is based on typical reproductive age for SCD where median survival is 42 years for men and 48 years for women.
You may not qualify if…
- Legally blind;
- Physically unable to complete the study questionnaires or the intervention;
- Report health history of hysterectomy, tubal ligation, medically or surgically induced menopause, or vasectomy that would
- Prevent ability to bear children;
- Report a desire to remain childless or have no further children;
- Report knowing or being a relative or friend of a participant previously enrolled in the study, or
- Previous participation in a CHOICES study.
Where it is running
- University of Florida — Gainesville, Florida, United States
Full record on ClinicalTrials.gov
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