Influence of Cannabidiol on Glucose Tolerance and The Gut Microbiota

Completed · Not applicable · Has a placebo group

Conditions studied: Diabetes

In brief

While many empirical projects have described multiple potential health benefits of CBD, the potential for CBD to provide protection against the development of diabetes via favorable modification of the gut microbiota has received relatively less attention. We hope to learn if CBD can improve glucose tolerance and the gut microbiota, and if these two improvements might be related.

Key facts

Study ID

NCT05285449

Run by

Christopher Bell

People needed

30

Starts

2022-02-09

Expected to finish

2024-05-31

Last updated by the study team

2024-07-03

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 18 years of age and older
• Weight more than 110 pounds
• Have a Body Mass Index greater than or equal to 25 kilograms/squared meters
• Free of gastrointestinal or metabolic diseases
• Sedentary (less than 150 minutes of moderate-intensity exercise per week during the previous 3 months)

You may not qualify if…

• Less than 18 years of age
• Pregnant or breastfeeding
• Have known food allergies
• Have been diagnosed with any autoimmune disorders or with compromised immune function
• Celiac disease
• Inflammatory bowel diseases
• Gastrointestinal cancers
• Diabetes
• Human Immunodeficiency Virus
• Adverse reaction to ingesting CBD oils, or CBD containing food products
• Taking any of the following medications will be excluded as these may have negative interactions with CBD:
• steroids,
• 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors,
• calcium channel blockers,
• antihistamines,
• human immunodeficiency virus antivirals
• immune modulators,
• benzodiazepines,
• antiarrythmics,
• antibiotics,
• anesthetics,
• antipsychotics,
• antidepressants,
• anti-epileptics,
• beta blockers,

Where it is running

• Colorado State University, Dept. of Health and Exercise Science — Fort Collins, Colorado, United States

Full record on ClinicalTrials.gov

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