Pectoral Nerve Blocks (PECs) for Cardiovascular Implantable Electronic Device Placement
Completed · Phase 2/Phase 3 · Has a placebo group
Conditions studied: Pain, Postoperative, Pain, Acute, Pain, Chest, Pain, Satisfaction, Patient, Opioid Use, Unspecified, Opioids; Harmful Use
In brief
The purpose of this study is to determine whether administration of a pectoral nerve blocks (Pecs I and II) with 0.25% bupivacaine are more effective as compared to placebo to provide analgesia for cardiac implantable electronic device (CIED) placement in cardiac electrophysiology lab
Key facts
- Study ID
- NCT05283980
- Run by
- Beth Israel Deaconess Medical Center
- People needed
- 62
- Starts
- 2022-11-17
- Expected to finish
- 2024-03-29
- Last updated by the study team
- 2026-07-30
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Patients 18 years of age or older
- Undergoing CIED placement in electrophysiology lab
- Booked with anesthesia service for the procedure.
You may not qualify if…
- Current participation in another interventional study
- Use of mechanical circulatory support device
- Emergent procedures
- Patients receiving other modalities of regional anesthesia like intrathecal morphine
- Chronic opioid use for chronic pain conditions with tolerance (total daily dose of an opioid at or more than 30 mg morphine equivalent for more than one month within the past year)
- Current use of SSRI, TCA, anti-epileptics, gabapentin, or pregabalin as part of multimodal pain management
- Hypersensitivity to bupivacaine
- Hemodynamics related: Oxygenation outside of normal limits (defined as PaO2 < 60mmHg on an FiO2 of 1.0 or SpO2 < 85% within 30 minutes prior to drug administration), Received an infusion or bolus ≥ 0.05 mcg/kg/min of epinephrine o Received an infusion or bolus ≥ 0.50 mcg/kg/min of milrinone, Received an infusion or bolus ≥ 0.20 mcg/kg/min of norepinephrine o Significant clinician or nursing concern, Hemodynamically unstable (defined as HR > 120, SBP < 80, MAP < 50 within 30 minutes prior to drug administration)
Where it is running
- BIDMC — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.