Sickle Cell Disease (SCD) Bone Pain Study

Running, not enrolling · Not applicable

Conditions studied: Sickle Cell Disease, Sickle Cell Anemia, Low Bone Density, Osteoporosis, Osteopenia, Vertebral Fracture, Vertebral Compression, Osteonecrosis, Ischemic Necrosis, Avascular Necrosis

In brief

A prospective study to determine how low bone mineral density and/or vertebral compression fractures associate with pain in adults with sickle cell disease

Key facts

Study ID

NCT05283148

Run by

University of California, Davis

People needed

53

Starts

2022-11-03

Expected to finish

2026-07-31

Last updated by the study team

2025-08-24

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18-80 years with SCD (any genotype, confirmed by hemoglobin electrophoresis or high performance liquid chromatography)
• Ability to provide written informed consent
• Ability to lay on a DXA scanner
• Negative urine pregnancy test for women of childbearing potential at study entry

You may not qualify if…

• Pregnant women
• Adults unable to consent
• Individuals who are not yet adults (infants, children, teenagers)
• Prisoners
• Hospitalizations (any cause) within 2 weeks of study entry

Where it is running

• UC Davis Comprehensive Cancer Center — Sacramento, California, United States

Full record on ClinicalTrials.gov

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