Medico-economic Evaluation of Management Strategies for Severe Epistaxis

Recruiting now · Not applicable

Conditions studied: Epistaxis

In brief

Current recommendations consider surgical ligation and supra-selective embolization as equivalent in terms of efficacy and there is no clear consensus to choose between one and the other technique. In the absence of medico-economic studies, these recommendations could not be based on any differences in efficiency between the two techniques. The management of patients with severe non-traumatic epistaxis remains controversial and varies according to the hospital and/or university centers. In practice, the use of one or the other technique depends on the habits of each reference center.

Key facts

Study ID: NCT05281952
Run by: University Hospital, Toulouse
People needed: 180
Starts: 2023-05-01
Expected to finish: 2026-12-01
Last updated by the study team: 2023-08-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Patient with severe epistaxis who failed treatment with double tamponade for more than 48 hours.
Patient over 18 years old
Affiliated patient or beneficiary of a social security scheme.
Patient accepting the principle of randomization
Free, informed and written consent, signed by the participant and the investigator (at the latest on the day of inclusion and before any examination required by the research).

You may not qualify if…

Patient with epistaxis secondary to facial and/or surgical trauma.
Patient with epistaxis related to a malignant tumor cause
Patient with a history of ligation or embolization
Patient under legal protection and/or curatorship and/or guardianship.
Impossibility of giving the person informed information and ensuring the subject's compliance due to impaired physical and/or psychological health.
Patient participating in another research including an exclusion period still in progress
Pregnant or breastfeeding patient
For non randomized patient
Patient with a contraindication to general anesthesia: severe and/or decompensated cardiac/hepatic/renal insufficiency, ASA score 4
Severe hemostasis disorders that cannot benefit from correction.
History of transient and/or definitive stroke of the ischemic type
Atheromatous overload

Where it is running

University Hospital — Toulouse, France (enrolling)

Full record on ClinicalTrials.gov

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