Correlation Between the Changes of Retinal Structure and Function and Ischemic Stroke
Recruiting now
Conditions studied: Ischemic Stroke
In brief
Ischemic stroke is the most common type of stroke, accounting for 60%-80% of all types of strokes, and is one of the leading global causes of death and severe disability. In the risk factors of stroke, carotid atherosclerosis have higher incidence.As the only visible microvessels in vivo, retinal can provides an accurate window into cerebrovascular and systemic vascular conditions. Optical coherence tomography angiography (OCTA) and electroretinogram (ERG) can be used to quantitatively analyze the retinal structure and function in patients with ischemic stroke, and find out the valuable parameters. Electroencephalogram(EEG) can collect the electrical activity of cerebral cortex in patients with ischemic stroke and find the correlation between EEG and ERG. Finally, it is of great significance to establish a non-invasive, more objective, convenient and safe risk prediction model for stroke in combination with carotid atherosclerosis, retinal structural and functional parameters and EEG.
Key facts
- Study ID
- NCT05281887
- Run by
- Guangdong Provincial People's Hospital
- People needed
- 120
- Starts
- 2021-12-01
- Expected to finish
- 2032-01-01
- Last updated by the study team
- 2022-08-09
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Patients with ischemic stroke
You may not qualify if…
- Refractive interstitial turbidity affect the examination results
- Any retinal diseases
- Other causes of ischemic stroke (cardiogenic embolism, dissection aneurysm, hemagglutination disorder, polycythemia, vasculitis, vascular malformation, etc.)
- Fails to complete an ophthalmic examination or the follow-up
Where it is running
- Guangdong Provincial People's Hospital — Guangzhou, Guangdong, China (enrolling)
Full record on ClinicalTrials.gov
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