Double-Blind Study Determining the Efficacy of CannaXR in Decreasing UVA Premutagenic and Photoaging Markers

Completed · Not applicable

Conditions studied: Photoaging

In brief

Ultraviolet light A (UVA) causes oxidization of guanine to mutagenic 8-Oxoguanine (8-OxoG) and the most frequent and best characterized mutation in mitochondrial DNA (mtDNA), a deletion of 4,977 base pairs, called the "common deletion", a marker of photoaging.

Key facts

Study ID

NCT05279495

Run by

MINO Labs, LLC

People needed

20

Starts

2023-01-15

Expected to finish

2023-05-15

Last updated by the study team

2025-05-08

Who can join

Age: 22 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy subjects
• 22-65 years of age
• Fitzpatrick skin types II and III

You may not qualify if…

• Pregnancy
• Personal history of skin cancer
• History of abnormal photosensitivity
• Tobacco smoker
• History or being exposed to other forms of radiation (other than sunlight)
• Using any drug/medication that might alter the response of skin to UVA irradiation
• Unable to undergo skin biopsies
• History of abnormal scarring
• History of exposure to the treated areas with external beam X-ray or non-solar UV light irradiation

Where it is running

• Center for Clinical and Cosmetic Research — Aventura, Florida, United States

Full record on ClinicalTrials.gov

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