Neurofeedback Based on Near-infrared Spectroscopy as a Therapy for Food Addiction in Obese Subjects.

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Obesity, Craving

In brief

The hypothesis is that the increase in dlPFC brain activity via near-infrared spectroscopy-based Neurofeedback (fNIRS-based NF) training based on near-infrared spectroscopy would allow an improvement of the eating behavior, thus promoting a long-term weight loss in obese subjects. Patients will be trained during a month with 8 NF sessions and results based on clinical data and different questionnaires results will be compared between inclusion and 3 months later

Key facts

Study ID

NCT05277714

Run by

Rennes University Hospital

People needed

50

Starts

2022-05-25

Expected to finish

2026-12-01

Last updated by the study team

2025-08-08

Who can join

Age: 18 and older, up to 55. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Eligible for obesity surgery according to the 2009 French High Authority on Health (HAS) criteria (BMI ≥40 or BMI ≥35 with comorbidities)
• Right-handed
• Presenting a food addiction determined by the YFAS 2.0 questionnaire ;
• Affiliated to a social security system;
• Having given free and informed consent in writing.

You may not qualify if…

• Psychotic psychiatric disorders (schizophrenic disorders and bipolar disorders);
• Psychotropic drugs, except antidepressants stabilized for at least 3 weeks and benzodiazepines
• Addiction to alcohol or other psychoactive substances (except tobacco);
• History of bariatric surgery;
• Current treatment in the nutrition unit;
• Insufficient command of French;
• Pregnant or breast-feeding woman;
• Persons of legal age under legal protection (safeguard of justice, curatorship, guardianship), persons deprived of liberty.
• Contraindications to fMRI
• Inability to perform the fNIRS procedure due to blockage or attenuation of the light at the capillary level

Where it is running

• CHU Rennes — Rennes, France (enrolling)

Full record on ClinicalTrials.gov

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