Coronary Microvascular Dysfunction Assessments in Myocardial Infarction With Non-Obstructive Coronary Arteries
Recruiting now
Conditions studied: Myocardial Infarction, Coronary Microvascular Dysfunction, Vasospasm, Coronary
In brief
To compare clinical outcomes of myocardial infarction with non-obstructive coronary arteries (MINOCA) according to the coronary microvascular dysfunction (CMD), evaluated by optical coherence tomography (OCT), invasive and non-invasive coronary physiologic assessment.
Key facts
- Study ID
- NCT05272618
- Run by
- Chonnam National University Hospital
- People needed
- 150
- Starts
- 2022-02-14
- Expected to finish
- 2030-12-31
- Last updated by the study team
- 2026-05-12
Who can join
Age: 19 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Subject with age ≥19 years and acute myocardial infarction
- Rise and/or fall of cardiac troponin with one level >99 percentile plus ischemic signs/symptoms
- Subject with non-obstructive coronary arteries
- <50% diameter stenosis or
- fractional flow reserve (FFR) >0.80 ③ Subject without previous history of coronary artery disease
- Subject who performed invasive coronary angiography within 24 hours after presentation ⑤ Subject who eligible for invasive and non-invasive coronary physiologic assessment
You may not qualify if…
- Subject with obstructive coronary arteries
- Subject with alternate diagnosis including sepsis, pulmonary embolism, myocarditis, Takotsubo syndrome, spontaneous coronary dissection, and other cardiomyopathies.
- Subject with cardiogenic shock or cardiac arrest ④ Subject who has non-cardiac co-morbid conditions with life expectancy <1 year ⑤ Subject or lactating women ⑥ Subject unable to provide consent
Where it is running
- Chonnam National University Hospital — Gwangju, Gwangju, South Korea (enrolling)
Full record on ClinicalTrials.gov
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