Conservative Management of Left Ventricular Assist Device Candidates
Recruiting now
Conditions studied: Advanced Heart Failure
In brief
Left ventricular assist device (LVAD) candidates will be comprehensively evaluated at our center, including clinical evaluation, echocardiography, right heart catheterization, cardiopulmonary exercise test and laboratory exams. following this evaluation, patients will be treated with inotropes, diuretics, uptitrated neurohormonal therapy. vitamin and iron deficiencies will be corrected and the patients will be referred for coronary interventions and cardiac resynchronization therapy appropriately. The need for LVAD implantation will be reevaluated according to the patient's clinical condition, echocardiography and laboratory findings.
Key facts
- Study ID
- NCT05271214
- Run by
- Tel-Aviv Sourasky Medical Center
- People needed
- 100
- Starts
- 2018-01-01
- Expected to finish
- 2028-01-01
- Last updated by the study team
- 2022-03-08
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- left ventricular ejection fraction <35%. New York Heart Association Class III or IV. Brain natriuretic peptide levels > 450pg/ml. Heart failure hospitalization in the past 6 months. Maximal oxygen consumption < 12 ml/kg/min. Intolerant to conventional heart failure therapy.
You may not qualify if…
- Special populations - pregnant, unable to give informed consent. Advanced liver disease (Child Pugh class B or C). Advanced kidney disease (eGFR<30ml/min). Severe pulmonary disease. Severe peripheral vascular disease. Active malignancy.
Where it is running
- Tel Aviv Sourasky Medical Center — Tel Aviv, Israel (enrolling)
Full record on ClinicalTrials.gov
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