Neuroimaging Reveals Treatment-related Changes in DLD
Recruiting now · Not applicable
Conditions studied: Developmental Language Disorder
In brief
Children with developmental language disorders (DLD, aka specific language impairment), a prevalent pediatric disorder, experience hallmark grammar deficits with life-long impacts on educational and occupational outcomes. While effective and early interventions can mitigate the impact of DLD, not enough is known about the neural basis of DLD in young children, yet is needed to inform the design of more individualized interventions. This project uses neuroimaging, along with behavioral methods, with the goal of better understanding the memory-language mechanisms that underlie grammar learning and impairment, while also considering their association to treatment-related changes in preschoolers with DLD.
Key facts
- Study ID
- NCT05268341
- Run by
- University of Cincinnati
- People needed
- 100
- Starts
- 2022-05-24
- Expected to finish
- 2027-06-30
- Last updated by the study team
- 2026-05-26
Who can join
Age: 4 and older, up to 6. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- ages 48-71 months
- average nonverbal intelligence quotient (IQ)
- enrolled in participating center
- typically developing (receptive and expressive language, social, articulation, other)
- DLD for expressive grammar
- typical oral motor function
- typical social/pragmatics skills
- average hearing thresholds
- monolingual and native Standard English speakers
- does not have any uncorrected vision challenges
You may not qualify if…
- receiving co-occurring speech-language or other intervention for communication
- not MRI safe
- special education placement of child based on ability or behavior
Where it is running
- Empower Learn Create INC — Cincinnati, Ohio, United States (enrolling)
- CWFF CHild Development Center — Cincinnati, Ohio, United States (enrolling)
- Wesley Education Center for Children and Families — Cincinnati, Ohio, United States (enrolling)
- University of Cincinnati — Cincinnati, Ohio, United States (enrolling)
- New Horizon Childcare — Cincinati, Ohio, United States
- Cincinnati Children's Hospital — Cincinnati, Ohio, United States
Full record on ClinicalTrials.gov
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