Exploring Cortical Remyelination in Children With Multiple Sclerosis
Recruiting now · Not applicable
Conditions studied: Children With Multiple Sclerosis
In brief
Multiple sclerosis (MS) in children, a rare disease, follows a relapsing remitting course with a shorter interval between the first 2 clinical events and higher annualized relapse rate as compared with MS in adults. Residual deficits following clinical events are less frequent. The vast majority of children and adolescents with MS are thought to have a greater potential for myelin repair than adults. However convincing data in the literature to support this hypothesis are lacking, because until now no imaging technique has been validated to measure remyelination in vivo.
Key facts
- Study ID
- NCT05258396
- Run by
- Assistance Publique - Hôpitaux de Paris
- People needed
- 40
- Starts
- 2022-08-11
- Expected to finish
- 2026-09-11
- Last updated by the study team
- 2026-03-06
Who can join
Age: 12 and older, up to 18. Sex: any. Healthy volunteers: accepted.
Where it is running
- Service de Neurologie Pédiatrique, Hôpital du Kremlin Bicêtre — Le Kremlin-Bicêtre, France (enrolling)
- CIC Neurosciences - Pitié Salpêtrière — Paris, France (enrolling)
- Service de Neurologie, GH Pitié Salpêtrière — Paris, France
Full record on ClinicalTrials.gov
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