Cortical Excitability in Cyclic Vomiting Syndrome

Recruiting now · Not applicable

Conditions studied: Cyclic Vomiting Syndrome

In brief

This exploratory study will determine if there are differences in cortical excitability between patients suffering from cyclic vomiting syndrome (CVS) and healthy control subjects, as assessed by a non-invasive method of brain stimulation (Transcranial Magnetic Stimulation, TMS).

Key facts

Study ID

NCT05256160

Run by

University of Pittsburgh

People needed

110

Starts

2022-05-16

Expected to finish

2027-06-01

Last updated by the study team

2025-08-24

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• diagnosis of CVS

You may not qualify if…

• history of CVS (for healthy control population only)
• psychosis or altered cognitive status
• history of head injury, metal in the skull, stroke, or a history of seizures or a history of syncope (fainting or passing out)
• implantable devices, such as a pacemaker or nerve stimulator
• current use of the following medications or use of substances which are known to lower the seizure threshold: clozapine (Clozaril), chlorpromazine (Thorazine), amphetamines or methamphetamine, Ecstasy, Ketamine, Angel Dust/PCP, cocaine, or 3 or more alcoholic drinks per day
• pregnancy

Where it is running

• University of Pittsburgh Medical Center — Pittsburgh, Pennsylvania, United States (enrolling)

Full record on ClinicalTrials.gov

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