Sex-related Differences in Sympathetic Vascular Transduction in the Setting of Hypoxemia

Completed · Early Phase 1 · Has a placebo group

Conditions studied: Vasodilation, Hypoxia

In brief

The purpose of this project is to identify sex-related differences in the effect of hypoxia on sympathetic vascular transduction.

Key facts

Study ID

NCT05256069

Run by

University of Missouri-Columbia

People needed

31

Starts

2023-04-26

Expected to finish

2025-07-31

Last updated by the study team

2025-09-15

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• healthy adult men and women;
• 18-45 years of age;
• BMI 18-30 kg/m2;
• non-pregnant/non-breastfeeding;
• non-nicotine users;

You may not qualify if…

• Pregnancy, breastfeeding, hormonal contraceptives
• Diagnosed sleep apnea
• Current smoking/Nicotine use/drug use
• Nerve/neurologic disease
• Cardiovascular, hepatic, renal, respiratory disease
• Blood pressure ≥140/90 mmHg
• Diabetes, Polycystic ovarian syndrome
• Communication barriers
• Prescription medications
• Recent COVID-19 diagnosis with symptoms

Where it is running

• University of Missouri-Columbia — Columbia, Missouri, United States

Full record on ClinicalTrials.gov

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