Transcranial Direct Current Stimulation Treatment for Warriors Experiencing Chronic Pain
Completed · Not applicable
Conditions studied: Chronic Pain, Post Traumatic Stress Disorder (PTSD), Depression
In brief
The Veteran population has been known to deal with co-morbid chronic pain and PTSD. As a result, they use healthcare services at a higher rate than those Veterans with pain or PTSD alone which leads to an amplified burden on healthcare systems. tDCS is a painless brain stimulation treatment that uses direct electrical currents (at a constant, low-intensity level) to stimulate specific parts of the brain and help modulate neuronal activity. This study hypothesizes that our short-term therapy-focused treatment program coupled with tDCS administrations will aid in the reduction of chronic pain and PTSD symptoms. Secondly, the investigators intend to examine any relationships between BDNF reduction in reported pain and PTSD and related mental health symptoms. Subjects will be identified from the Emory Healthcare Veterans Program (EHVP-IOP) Veterans and Service members seeking psychiatric treatment for mental health issues including PTSD.
Key facts
- Study ID
- NCT05254379
- Run by
- Emory University
- People needed
- 38
- Starts
- 2022-03-04
- Expected to finish
- 2025-05-31
- Last updated by the study team
- 2025-09-11
Who can join
Age: 18 and older, up to 89. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Male or Female, 18 -89 years old
- Treated on site for EHVP IOP
- For long-term follow-up, must live in Georgia or Florida
- Eligible for EHVP-IOP PTSD or Unified Protocol tracks
- Willing to self-administer tDCS and complete the measures
- DVPRS pain intensity of 4 or more for most of the day at least 3 days per week
- Have an established PCP (Primary Care Provider) or pain management provider
You may not qualify if…
- Implanted pacemaker
- Seizure Disorder
- Pregnancy, if applicable
- Any new onset of the following:
- Balance problems
- Difficulty walking
- Bladder incontinence
- Bowel incontinence
- Numbness
- Tingling
- Weakness
- Medical contraindications:
- Current use of sodium channel blockers
- Lidocaine (OTC/transdermal delivery is ok)
- Mexiletine
- Amitriptyline; other tricyclic antidepressants
- Anti-epileptic medications
- Phenytoin, carbamazepine, lamotrigine, oxcarbazepine, rufinamide, lacosamide and eslicarbazepine acetate
- Current use of calcium channel blockers
- Current use of N-Methyl-D-aspartate receptor antagonists
- Ketamine
- Dextromethorphan
- Felbamate
- History of brain surgery
- History of brain tumor
Where it is running
- Emory Division of Psychiatry — Atlanta, Georgia, United States
Full record on ClinicalTrials.gov
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