The Effect of Structured Lifestyle Modification and Yoga Practice on Metabolic Processes Associated With Cardiovascular Disease

Stopped early · Not applicable

Conditions studied: Coronary Artery Disease

In brief

The aim of the prospective randomized single center study is to evaluate the effect of a short-term (16 weeks) yoga program on micro RNA (miRNA) expression and cardiovascular disease (CVD) risk factors in patients with CVD.

Key facts

Study ID

NCT05250310

Run by

Icahn School of Medicine at Mount Sinai

People needed

16

Starts

2022-01-24

Expected to finish

2025-10-24

Last updated by the study team

2026-02-11

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subjects eligible for the study are 18-80 year old adults.
• Underwent percutaneous coronary intervention (PCI) at the catheterization lab of Mount Sinai Hospital (New York, New York) or have non-obstructive coronary artery disease and at least one CVD risk factor (hypertension, hypercholesterolemia, diabetes mellitus, or obesity) or metabolic abnormality (fasting plasma glucose ≥ 100 mg/dl, documented previous diagnosis of hypertension, serum triglycerides ≥ 150 mg/dl, or HDL cholesterol < 40 mg/dl).
• Subjects diagnosed with metabolic syndrome, which is defined as three or more of the following conditions: (1) Central or abdominal obesity (waist circumference > 40 inches for men and > 35 inches for women); (2) High triglycerides (≥150 mg/dL or triglycerides treatment); (3) Low HDL cholesterol (<40 mg/dL for men and <50 mg/dL for women) or low HDL-C treatment; (4) High blood pressure (≥130/85 mmHg) or antihypertensive medications; (5) High fasting glucose (≥100 mg/dL) or type 2 diabetes mellitus.
• Participants must be able to willingly consent to study participation and must be able to comply with the study requirements.

You may not qualify if…

• Physical/psychological limitation or unwillingness to practice yoga,
• Congestive heart failure, known arrthymias or prior Automated Implantable Cardioverter-Defibrillator /pacemaker or any metallic implants,
• Rheumatological/immunological diseases,
• History of transplant,
• Moderate to severe chronic obstructive pulmonary disease, debilitating or severe systemic Illness,
• Subjects who are pregnant or postpartum less than 6 months,
• Liver disease or alcohol use of more than 7 alcoholic drinks/week in women and more than 14 drinks/week in men

Where it is running

• Mount Sinai Hospital — New York, New York, United States

Full record on ClinicalTrials.gov

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