4D-710 in Adult Patients With Cystic Fibrosis

Recruiting now · Phase 2

Conditions studied: Cystic Fibrosis Lung

In brief

This is a Phase 1/2 multicenter, open-label, single dose trial of 4D-710 investigational gene therapy in adults with cystic fibrosis.

Key facts

Study ID

NCT05248230

Run by

4D Molecular Therapeutics

People needed

30

Starts

2022-03-29

Expected to finish

2031-06-01

Last updated by the study team

2026-07-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• University of Washington Medical Center — Seattle, Washington, United States (enrolling)
• The University of Arizona — Tucson, Arizona, United States (enrolling)
• University of California San Francisco — San Francisco, California, United States (enrolling)
• National Jewish Health — Denver, Colorado, United States (enrolling)
• University of Florida — Gainesville, Florida, United States (enrolling)
• University of Miami Hospital — Miami, Florida, United States (enrolling)
• Northwestern Memorial Hospital — Chicago, Illinois, United States (enrolling)
• University of Kansas Medical Center — Kansas City, Kansas, United States (enrolling)
• Johns Hopkins Hospital — Baltimore, Maryland, United States (enrolling)
• Massachusetts General Hospital — Boston, Massachusetts, United States (enrolling)
• Boston Children's Hospital — Boston, Massachusetts, United States (enrolling)
• Virginia Commonwealth University Health System — Richmond, Virginia, United States (enrolling)
• University of Alabama Child Health Research Unit — Birmingham, Alabama, United States (enrolling)
• Rainbow Babies and Children's Hospital/University Hospitals Cleveland Medical Center — Cleveland, Ohio, United States (enrolling)
• Nationwide Children's Hospital — Columbus, Ohio, United States (enrolling)
• The Hospital of the University of Pennsylvania — Philadelphia, Pennsylvania, United States (enrolling)
• Medical University of South Carolina — Charleston, South Carolina, United States (enrolling)
• The University of Texas Southwestern Medical Center — Dallas, Texas, United States (enrolling)
• University of North Carolina at Chapel Hill — Chapel Hill, North Carolina, United States
• Penn State Health — Hershey, Pennsylvania, United States

Full record on ClinicalTrials.gov

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