Evaluation of the Impact of Reduced Immunosuppression

Completed

Conditions studied: Graft Vs Host Disease

In brief

Graft-versus-host disease (GVHD) is a life-threatening complication of transplantation. It occurs when the donor graft contains immunologically competent T-cells that recognize the recipient as foreign.

Key facts

Study ID

NCT05238155

Run by

Methodist Health System

People needed

100

Starts

2021-10-19

Expected to finish

2025-07-29

Last updated by the study team

2026-03-23

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• ≥ 18 years
• Received OLT or Combined Kidney-Liver Transplant(CKLT) during study period

You may not qualify if…

• Recipients requiring re-transplant within one month post-transplant
• Recipients who died of a cause other than GVHD within one month post-transplant

Where it is running

• Methodist Dallas Medical Center — Dallas, Texas, United States

Full record on ClinicalTrials.gov

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