COcoa Supplement and Multivitamin Outcomes Study: Effects on Falls and Physical Performance

Running, not enrolling · Not applicable · Has a placebo group

Conditions studied: Fall, Physical Performance, Fracture

In brief

The COcoa Supplement and Multivitamin Outcomes Study (COSMOS; NCT02422745) is a randomized clinical trial of cocoa extract supplement (containing a total of 500 mg/d flavanols, including 80 mg. (-)-epicatechins), and a standard multivitamin supplement to reduce the risk of cardiovascular disease and cancer among men aged 60 years and older and women aged 65 years and older. This ancillary study is being conducted among participants in COSMOS and will examine whether the cocoa extract supplement or the multivitamin supplement improve musculoskeletal health and prevent falls and declining physical performance in the increasing number of older adults in the U.S. with potential for clinical and public health benefits.

Key facts

Study ID
NCT05232669
Run by
Brigham and Women's Hospital
People needed
21442
Starts
2021-05-15
Expected to finish
2027-02-01
Last updated by the study team
2026-04-13

Who can join

Age: 60 and older. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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