3D OPTIMIZED WMN MPRAGE Increased Detection of Focal Spinal Cord Lesion in Multiple Sclerosis (WHINUME)

Recruiting now · Not applicable

Conditions studied: Multiple Sclerosis

In brief

The aim of this study is to compare the 3D OPTIMIZED MPRAGE WMN sequence to "conventional sequences" used in spinal cord analysis. The patients will be explored at the cervical level with the conventional 2D sagittal T2 FSE, 2D sagittal STIR, 2D sagittal PSIR, 3D T1 MPRAGE sequences, and the sequence of interest 3D sagittal OPTIMIZED WMN MPRAGE and 3D axial OPTIMIZED WMN MPRAGE. At the thoracic level, with the conventional 2D sagittal T2 FSE, 2D sagittal STIR, 3D T1 MPRAGE sequences and the sequence of interest 3D sagittal OPTIMIZED WMN MPRAGE.

Key facts

Study ID

NCT05227092

Run by

University Hospital, Bordeaux

People needed

60

Starts

2023-08-02

Expected to finish

2026-05-01

Last updated by the study team

2025-06-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients older than 18 years old
• CIS or RRMS
• Medullary symptomatology less than 6 months
• With or without an objective lesion on a subsequent MRI scan
• Signed the Informed Consent

You may not qualify if…

• Pregnant or potentially pregnant women
• Breastfeeding woman
• Contraindications to MRI
• Other diagnosis (Neuro-myelitis spectrum disease or Progressive Multiple Sclerosis)
• Surgical history on the spinal cord or lumbar spine
• Patient under legal protection

Where it is running

• CHU de Bordeaux — Bordeaux, France (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.