MRD Assay Evaluates Recurrence and Response Via a Tumor Informed Assessment
Running, not enrolling
Conditions studied: Cancer, Solid Tumor, Non Small Cell Lung Cancer, Colorectal Cancer, Bladder Cancer
In brief
This study recruits patient with solid tumor types for sample collection and monitoring. Participants will provide blood and archival tissue samples in order to create a Personalized Cancer Monitoring (PCM) assay. This assay will be used to detect circulating tumor DNA (ctDNA) levels in the blood over time and hopefully contribute to improvements in residual disease detection methods for future patients. Results from this assay will be provided to participants and providers but providers are not asked to change patient care based on this information.
Key facts
- Study ID
- NCT05219734
- Run by
- Invitae Corporation
- People needed
- 400
- Starts
- 2021-11-29
- Expected to finish
- 2026-12-01
- Last updated by the study team
- 2024-03-12
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Stated ability to give informed consent by participant.
- Stated health status of participant as healthy enough to provide Biological Material.
- Individuals diagnosed with solid cancer of any type, including but not limited to colorectal, non-small cell lung, breast, ovarian and bladder cancers, regardless of the length of time since diagnosis and regardless of previous therapies.
- Participant is of any biological sex and >18 years of age
- Participant has not undergone a blood transfusion within the previous three weeks
You may not qualify if…
- Participants who are deemed medically unstable
- Participants who are deemed to be "difficult to draw" blood from.
- Participants who are <18 years of age
- Participants diagnosed with CNS cancers, sarcomas or hematologic malignancies such as leukemia or lymphoma .
- Participants with more than one primary cancer
- Participants with FFPE slides older than 10 years
- Participants who are pregnant
- Any other reason that, in the Investigator's judgment, that would preclude the participant from being able to participate in the study
- Participants for which a pathology report is not available
Where it is running
- Columbus Regional Health — Columbus, Indiana, United States
- Onslow Radiation — Jacksonville, North Carolina, United States
Full record on ClinicalTrials.gov
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