Language Acquisition in the Brain and Algorithms: Towards Systematic Monitoring of the Evolution of Semantic Representations in Biological and Artificial Neural Networks

Recruiting now

Conditions studied: Language Acquisition in the Brain

In brief

Speech depends on our ability to recursively combine successive words into a complex sense. Although the order of these putative operations (syntax) has been the subject of extensive examination in the way in which the human brain learns to perform a "Semantic composition" remains largely unknown. The Rothschild Hospital houses a unit specializing in drug-resistant epilepsy in children from 2 to 20 years old. The identification of the epileptogenic zone often requires making an iEEG recording for a week (implantation of intracerebral electrodes in depth). Sometimes this recording has to be repeated, providing a unique opportunity to directly record brain activity at different periods of its development. Children will listen to pre-recorded phrases and stories such as "The Little Prince of Antoine de Saint-Exupéry" while being recorded with iEEG.

Key facts

Study ID

NCT05217043

Run by

Fondation Ophtalmologique Adolphe de Rothschild

People needed

100

Starts

2022-07-15

Expected to finish

2027-02-15

Last updated by the study team

2026-01-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Any patient benefiting from a long-term intracranial brain recording.
• Non-opposition to participating in the study (adult patients)
• Non-opposition of at least one of the holders of the exercise of parental authority (minor patients)

You may not qualify if…

• Patient with complete deafness

Where it is running

• Fondation Ophtalmologique de Rothschild — Paris, France, France (enrolling)

Full record on ClinicalTrials.gov

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