Treatment of Ocular Demodex Infestation With Topical Ivermectin Cream 1%

Status unconfirmed · Phase 1

Conditions studied: The Focus of the Study is to Assess the Effectiveness of Topical Ivermectin on Eliminating Eyelash Sleeves

In brief

Patients with Demodex infestation of the eyelids will have the sleeves from both eyes cleaned off with microblepharoexfoliation. Afterwards, one eye will be randomly selected for treatment with topical ivermectin 1% cream. The treatment will be repeated on that eye 2 weeks later. Afterwards, the patients will present monthly for photographs of the eyelashes. The photographs will be reviewed by an ophthalmologist outside of our institution who will be blind to which eye was treated and independently grade the amount of sleeves in each eye. The follow-up will be for 6 months after the second treatment.

Key facts

Study ID
NCT05213585
Run by
Helm Vision Group
People needed
20
Starts
2021-08-24
Expected to finish
2022-12-31
Last updated by the study team
2022-01-28

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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