DNA Sequencing in Clinical Practice, Mayo Clinic Health Tapestry Study
Running, not enrolling · Not applicable
Conditions studied: Genetic Disorder
In brief
This clinical trial collects information on how sequencing a patient's deoxyribonucleic acid (DNA) (i.e., the genetic material) could impact their health care. This study also develops and improves ways to include genomic information from DNA sequencing into the electronic health record to create a more complete "Health Tapestry" for each participant. Sequencing of a patient's DNA leads to the detection of genetic variants some of which determine risk for disease development. Discovery of those genetic variants in a patient could result in prevention, earlier diagnosis or better therapy of disease.
Key facts
- Study ID
- NCT05212428
- Run by
- Mayo Clinic
- People needed
- 110000
- Starts
- 2020-01-22
- Expected to finish
- 2029-11-30
- Last updated by the study team
- 2026-06-10
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age >= 18 years
- Registered Mayo Clinic patient
- Able to provide informed written consent
- E-mail and web access (for electronic consent, video education, registering with Helix and receiving results)
- Ability to collect and ship saliva sample within the United States
- Of note: Women, who are pregnant, or planning to become pregnant, can take part in this study. However, this study does not replace prenatal genetic testing. If participants have these concerns, they will be encouraged to contact their obstetrics (OB) provider or a genetic counselor to discuss further
You may not qualify if…
- Other co-morbidity which would in physician's opinion interferes with patient's ability to participate in the study (eg: reduced ability to comprehend eg: dementia, intellectual disability, fluency in consent language)
- Allogeneic bone marrow transplant (e.g. samples from autologous bone marrow transplant recipients are acceptable if collected at least one month after transplant)
- Active hematological cancer or history of a hematological cancer
- Resident of the state of New York
- The Helix lab does not currently have New York state licensure
- Residents without a shipping address in the United States
- The Helix lab is unable to ship and receive samples internationally
Where it is running
- Mayo Clinic in Arizona — Scottsdale, Arizona, United States
- Mayo Clinic in Florida — Jacksonville, Florida, United States
- Mayo Clinic in Rochester — Rochester, Minnesota, United States
Full record on ClinicalTrials.gov
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