The Role of Surgery in Patients With Coronavirus Disease - 19 (COVID-19) Related Thoracic Complications

Completed

Conditions studied: Surgical Complication, COVID-19, Pneumothorax, Empyema, Pleural, Abscess, Hemothorax, Thoracic

In brief

Thoracic complications directly or indirectly consequence of Coronavirus Disease 2019 (COVID-19) (including either pathologies strictly related to the infection, or iatrogenic effects of therapeutic attempts to treat it) have been described during the pandemic. Many of the above conditions often require a surgical approach but, based on published data reporting high early postoperative morbidity and mortality, many experts initially advised against any referral to surgery in COVID-19 patients. Therefore, the issue is if salvage surgical approach should be always excluded or could be considered when it represents the only remaining effective option. In the absence of solid data and recommendations, this is a demanding challenge for thoracic surgeons. The investigators have coordinated a multicenter study to collect the experience of several worldwide high-volume thoracic surgery departments. Their objective is to investigate efficacy and safety of surgery in COVID-19 patients who developed thoracic complications that required operative management.

Key facts

Study ID

NCT05204537

Run by

University of Milano Bicocca

People needed

83

Starts

2020-03-01

Expected to finish

2022-03-30

Last updated by the study team

2023-05-30

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age > 18 years old;
• molecular diagnosis of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection through nose-pharyngeal swab or bronchoalveolar lavage via real-time polymerase chain reaction (PCR) analysis;
• hospital admission because of clinical/radiological diagnosis of pneumonia;
• onset of thoracic complications during hospitalization or prolonged hospitalization requiring thoracic surgical procedures;
• hospital admission from 01/03/2020 to 31/05/2021.

Where it is running

• San Gerardo Hospital — Monza, Italy
• Thoracic Surgery, NYU Langone Health — New York, New York, United States
• Thoracic Surgery, Hospital Federal do Andaraí — Rio de Janeiro, Brazil
• Sunrise hospital. — Kochi, India
• Thoracic Surgery, Sir Ganga Ram Hospital — New Delhi, India
• Thoracic Surgery, ASST Spedali Civili — Brescia, Italy
• Thoracic Surgery, San Camillo Forlanini Hospital. — Roma, Italy
• Thoracic Surgery, San Giovanni Battista Molinette Hospital — Turin, Italy
• Thoracic Surgery, University College London Hospitals — London, United Kingdom

Full record on ClinicalTrials.gov

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