Interventions in Mathematics and Cognitive Skills

Recruiting now · Not applicable

Conditions studied: Math Learning Disability, Child Development, Developmental Disability, Learning Disabilities, Learning Disabled, Learning Curve, Mathematics Disorder, Dyscalculia, Dyscalculia, Primary, Dyscalculia, Acquired, Specific Learning Disorder, With Impairment in Mathematics, Individuality, Behavior, Child, Behavior and Behavior Mechanisms, Behavior, Decision Making, Neuronal Plasticity, Cognition, Cognition Disorder, Cognitive Dysfunction, Cognitive Change, Cognitive Impairment, Mild, Cognitive Developmental Delay, Cognitive Orientation, Cognitive Delay, Mild, Cognitive Deficits, Mild, Cognitive Abnormality, Neuroscience

In brief

The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing, and remediating weaknesses in, numerical skills in children, including those with mathematical learning disabilities (MLD).

Key facts

Study ID

NCT05201534

Run by

Stanford University

People needed

180

Starts

2023-05-05

Expected to finish

2026-08-31

Last updated by the study team

2026-06-25

Who can join

Age: 6 and older, up to 12. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Elementary school aged children starting from first grade (6-12 years old)
• IQ: Participants with a Full Scale IQ > 70 on the Wechsler Abbreviated Scle of Intelligence (WASI-II).
• Identification of Mathematical Learning Disabilities: Scores below the 35th percentile percentile on symbolic number processing test in Numeracy Screener and two or more Wechsler Individual Achievement Test (WIAT-IV) math subtests
• Identification of typically developing children: Scores at or above the 35th percentile percentile on symbolic number processing test in Numeracy Screener and all WIAT-IV math subtests
• Normal or corrected-to-normal vision and no hearing impairments
• Inclusion in MRI scan session: Right-handed

You may not qualify if…

• History of neurological or psychiatric disorder (i.e., schizophrenia, psychosis, depression, or attention deficit hyperactivity disorder.)
• History of trauma involving head injury
• Consistent psychiatric medications
• Exclusion from MRI scan session: No major contraindication for magnetic resonance imaging (MRI) - braces, metal implants, pacemakers, vascular stents, metallic ear tubes, consistent exposure to metal, claustrophobia)

Where it is running

• Stanford Cognitive and Systems Neuroscience Laboratory — Palo Alto, California, United States (enrolling)

Full record on ClinicalTrials.gov

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