Phase 1/2 Study of ZN-d5 for the Treatment of Relapsed or Refractory Light Chain (AL) Amyloidosis

Completed · Phase 1/Phase 2

Conditions studied: Amyloidosis, AL Amyloidosis

In brief

This is a single arm, Open-Label, Phase 1/2 Study of ZN-d5 for the Treatment of Relapsed or Refractory Light Chain (AL) Amyloidosis.

Key facts

Study ID

NCT05199337

Run by

K-Group Alpha, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc.

People needed

18

Starts

2021-11-30

Expected to finish

2024-02-14

Last updated by the study team

2024-09-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• University of Southern California — Los Angeles, California, United States
• Colorado Blood Cancer Institute — Denver, Colorado, United States
• Tulane University — New Orleans, Louisiana, United States
• Washington University — St Louis, Missouri, United States
• Tennessee Oncology — Nashville, Tennessee, United States
• Blackwater (Westmead) Hospital — Westmead, New South Wales, Australia
• Princess Alexandra Hospital — Brisbane, Queensland, Australia
• Royal Adelaide Hospital — Adelaide, South Australia, Australia
• Sir Charles Gairdner Hospital — Nedlands, Western Australia, Australia
• Bank of Cyprus Hospital — Nicosia, Cyprus
• National and Kapodistrian University of Athens — Athens, Greece
• Rambam Hospital — Haifa, Israel
• Hadassah Medical Center — Jerusalem, Israel
• Sheba Medical Center — Tel Aviv, Israel
• Tel Aviv Sourasky Medical Center PPDS — Tel Aviv, Israel
• IRCCS Azienda Ospedaliero Universitaria di Bologna Policlinico Sant'Orsola Malpighi — Bologna, Italy
• Fondazione I.R.C.C.S. Policlinico San Matteo — Pavia, Italy
• ICO Badalona-H.U. Germans Trias i Pujol — Barcelona, Badalona, Spain
• Hospital Clínico Universitario Virgen de la Arrixaca — El Palmar, Murcia, Spain
• Hospital Clinic de Barcelona — Barcelona, Spain
• Clinico de Salamanca — Salamanca, Spain

Full record on ClinicalTrials.gov

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