Aerobic vs Resistance Exercise in Post-menopausal Women With Type 1 Diabetes

Recruiting now · Not applicable

Conditions studied: Type 1 Diabetes, Post-menopause

In brief

Participants will be asked to wear a continuous glucose monitor for at least three days on three separate occasions. One testing session will be a no-exercise resting control session (90 minutes). One will be a moderate aerobic exercise session (30 minutes of exercise, 60 minutes of recovery), and the third will be a moderate weight-lifting session (\~30 minutes of exercise, 60 minutes of recovery).The investigators will measure changes in blood glucose during exercise by drawing blood during and after exercise. Post-exercise glucose trends will be examined using continuous glucose monitoring.

Key facts

Study ID

NCT05188027

Run by

University of Alberta

People needed

20

Starts

2021-11-16

Expected to finish

2027-03-30

Last updated by the study team

2026-03-16

Who can join

Age: 45 and older, up to 75. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• type 1 diabetes, diagnosed for at least one year
• post-menopause (at least one year since last menstrual period), or have had a hysterectomy and bilateral salpingo oophorectomy
• able to perform aerobic and resistance exercise
• able to visit the lab in Edmonton, Alberta (University of Alberta)

You may not qualify if…

• HbA1c > 9.9 %
• frequent and unpredictable hypoglycemia
• change in insulin management strategy within the last 2 months
• blood pressure > 140 / 95
• severe peripheral neuropathy
• history of cardiovascular disease
• musculoskeletal injuries interfering with exercise performance
• use of medications (other than insulin) that affect glucose metabolism
• BMI > 30 kg/m2
• smoking
• moderate to high alcohol intake (> 2 drinks/day)

Where it is running

• Alberta Diabetes Institute — Edmonton, Alberta, Canada (enrolling)
• Institut de recherches cliniques de Montréal — Montreal, Quebec, Canada (enrolling)

Full record on ClinicalTrials.gov

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