Efficacy and Safety Study of Orvepitant for Chronic Cough in Patients With Idiopathic Pulmonary Fibrosis
Completed · Phase 2 · Has a placebo group
Conditions studied: Cough, Idiopathic Pulmonary Fibrosis
In brief
ORV-PF-01 is a two way, placebo controlled, cross-over study, to evaluate the effect of two doses of orvepitant on cough in patients with IPF.
Key facts
- Study ID
- NCT05185089
- Run by
- Nerre Therapeutics Ltd.
- People needed
- 80
- Starts
- 2022-08-01
- Expected to finish
- 2024-06-19
- Last updated by the study team
- 2025-11-10
Who can join
Age: 40 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Guy's Hospital — London, United Kingdom
- University of Southern California — Los Angeles, California, United States
- University of California — San Francisco, California, United States
- National Jewish Health — Denver, Colorado, United States
- Loyola University Chicago — Maywood, Illinois, United States
- Jadestone Clinical Research, LLC — Silver Spring, Maryland, United States
- University of Michigan — Ann Arbor, Michigan, United States
- Mayo Clinic — Rochester, Minnesota, United States
- American Health Research — Charlotte, North Carolina, United States
- PulmonIx, LLC — Greensboro, North Carolina, United States
- Temple University — Philadelphia, Pennsylvania, United States
- Medical University of South Carolina — Charleston, South Carolina, United States
- Vanderbilt University Medical Center — Nashville, Tennessee, United States
- Baylor University — Dallas, Texas, United States
- Clear Lake Health — Webster, Texas, United States
- University of Utah — Salt Lake City, Utah, United States
- University of Virginia Health System — Charlottesville, Virginia, United States
- Zuyderland Medical Centre — Heerlen, Netherlands
- Sint Antonius Hospital — Nieuwegein, Netherlands
- Erasmus University Medical Centre — Rotterdam, Netherlands
- Isala Ziekenhuis — Zwolle, Netherlands
- Royal Berkshire Hospital — Reading, Berkshire, United Kingdom
- Castle Hill Hospital — Cottingham, Hull, United Kingdom
- MAC Clinical Research — Prescot, Merseyside, United Kingdom
- Antrim Area Hospital — Antrim, Northern Ireland, United Kingdom
Full record on ClinicalTrials.gov
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