Spinal Cord Stimulation for Parkinsonism

Recruiting now · Not applicable

Conditions studied: Parkinsonism

In brief

Spinal Cord Stimulation (SCS) is a newly emerged neuromodulation technique in recent years. It is now a mature technique in the treatment of chronic pain and is generally accepted by patients because of its non-destructive and reversible nature, few complications, no side effects, and avoidance of unnecessary surgical procedures. Combining the results of previous studies and the group's previous research, this study first proposes an innovative treatment protocol for PDS with SCS. We intend to conduct a prospective single-center open clinical trial to evaluate the improvement of orthostatic hypotension, urinary retention, sleep disturbance, dysarthria, and dysphagia in Parkinsonism (PDS) patients before and after SCS treatment, and shed new light on the treatment for PDS.

Key facts

Study ID: NCT05171205
Run by: Ruijin Hospital
People needed: 50
Starts: 2021-05-01
Expected to finish: 2026-12-31
Last updated by the study team: 2025-05-09

Who can join

Age: 50 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Diagnosed with parkinsonism according to MDS clinical diagnostic criteria for Parkinson's disease
Aged between 50 and 80 years
Able and willing to follow instruction of the researcher
No other conditions that the researchers consider inappropriate for inclusion

You may not qualify if…

Severe depression (HAMD-17 above 17 as moderate to severe) or anxiety
Pregnancy
History of alcoholism
Non-neurological disease-related symptoms that prevent patients from participation in the study

Where it is running

Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine — Shanghai, Shanghai Municipality, China (enrolling)

Full record on ClinicalTrials.gov

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