Radio-opaque Contrast Agents for Liver Cancer Targeting With KIM During Radiation Therapy

Recruiting now

Conditions studied: Liver Neoplasm

In brief

This observational study will investigate the properties of image files standardly collected during radiation therapy treatment in a cross-section of liver cancer patients who received stereotactic ablative body radiation therapy (SABR) after trans-catheter arterial chemo emobilisation (TACE). Specifically, it will determine whether the radio-opaque contrast agents in the image files can be detected by tumour-tracking software (KIM).

Key facts

Study ID

NCT05169177

Run by

University of Sydney

People needed

50

Starts

2022-10-17

Expected to finish

2026-10-31

Last updated by the study team

2026-05-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Received or will receive stereotactic ablative body radiotherapy (SABR) treatment for liver cancer at a participating site.
• Received a radio-opaque contrast agent (e.g. Lipiodol™ or DC Bead LUMI™) that is visible on the radiation treatment planning CT scan
• The radio-opaque contrast agent mass is or will be within the x-ray imaging field of view during the CBCT scan and any planned intra-fraction imaging. Note that there is no requirement of the distance between the contrast agent mass and the treated tumour as the goal of the study is the contrast agent mass tracking.
• Provides written informed consent (prospectively recruited) or meets criteria for waiving of the requirement for consent (retrospectively recruited)

You may not qualify if…

• Less than 18 years of age
• Minimum image dataset is not available
• Image dataset is not in a compatible format

Where it is running

• Princess Alexandra Hospital — Woolloongabba, Queensland, Australia (enrolling)
• Calvary Mater Newcastle Hospital — Waratah, New South Wales, Australia
• Westmead Hospital — Westmead, New South Wales, Australia
• Peter MacCallum Cancer Centre — Melbourne, Victoria, Australia
• The Austin Hospital — Melbourne, Victoria, Australia

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.