Cardiac Magnetic Resonance Tissue Characterization in COVID-19 Survivors
Recruiting now
Conditions studied: COVID-19 Pneumonia, COVID-19, COVID-19 Respiratory Infection, COVID-19 Acute Respiratory Distress Syndrome, COVID-19 Lower Respiratory Infection, COVID-19 Acute Bronchitis, Coronavirus Disease 2019
In brief
The purpose of this study is to test if visualizing the heart with cardiac MRI/echo will be important in the understanding cardiac function and prediction of cardiopulmonary symptoms, physical effort tolerance, and outcomes in COVID-19 survivors. If successful, the research will allow us to identify the causes of lasting cardiopulmonary symptoms and begin developing cardiac and lung directed therapies accordingly.
Key facts
- Study ID
- NCT05164744
- Run by
- Weill Medical College of Cornell University
- People needed
- 510
- Starts
- 2021-07-01
- Expected to finish
- 2026-07-30
- Last updated by the study team
- 2026-01-22
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Emergency room presentation and/or hospitalization with COVID-19 infection defined in accordance with established criteria as follows: SAR-CoV2 RT-PCR+ (severe acute respiratory syndrome coronavirus 2 reverse transcription polymerase chain reaction) and at least one of the following symptoms: dyspnea, cough, dysphagia, rhinorrhea, diarrhea, nausea/vomiting, myalgias, fever, syncope/presyncope.
You may not qualify if…
- Contraindication to CMR (i.e. non-compatible pacemaker/defibrillator) or gadolinium (known hypersensitivity, eGFR (estimated globular filtration rate) <30 ml/min/1.73m2).
- Inability to provide informed consent (e.g. cognitive impairment).
- Unrelated condition (e.g. neoplasm) with life expectancy <12 months prohibiting follow-up.
- Patients with contraindications to gadolinium (known or suspected hypersensitivity, glomerular filtration rate < 30 ml/min/1.73m2) will undergo non-contrast MRI but will not be excluded from this study.
- Patients with known or suspected pregnancy based on Weill Cornell Radiology intake surveys (reviewed by a clinical RN (registered nurse), as well as research personnel) will be excluded from the protocol.
Where it is running
- New York Presbyterian-Brooklyn Methodist Hospital — Brooklyn, New York, United States (enrolling)
- New York Presbyterian Queens — New York, New York, United States (enrolling)
- Weill Cornell Medicine/New-York Presbyterian Hospital — New York, New York, United States (enrolling)
Full record on ClinicalTrials.gov
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