The Acute Cardiorespiratory Response to Blood-flow Restricted Versus Traditional Exercise Training Regimens (CaRe BFR)
Recruiting now · Not applicable
Conditions studied: COPD
In brief
The investigators hypothesize that BFR exercise regimens result in a different acute cardiorespiratory response pattern compared to traditional exercise regimens. Furthermore, the investigators hypothesize that these patterns differ between healthy participants and participants with COPD. Regarding secondary objective, the investigators hypothesize that BFR results in lower blood pressure responses compared to traditional exercise training in both healthy and COPD participants.
Key facts
- Study ID
- NCT05163600
- Run by
- University of Zurich
- People needed
- 24
- Starts
- 2022-05-20
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2026-07-07
Who can join
Age: 18 and older, up to 90. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Age ≥ 18 years
- Clinically healthy
You may not qualify if…
- Physical or intellectual impairment precluding informed consent or protocol adherence
- Non-German speaking (precluding informed consent)
- Pain during exercise of any origin
- Pregnancy
- History of thromboembolic event in the lower extremity
- Resting systolic blood pressure <100 mmHg
- Inclusion and exclusion for the COPD participants are defined by the following criteria.
- Inclusion criteria:
- Age ≥ 18 years
- Diagnosed COPD according to GOLD-guidelines12
- Exclusion criteria:
- Physical or intellectual impairment precluding informed consent or protocol adherence
- Non-German speaking (precluding informed consent)
- Acute or recent (within the last 6 weeks) exacerbation of COPD
- Pain during exercise of any origin
- Pregnancy
- History of thromboembolic event in the lower extremity
- Resting systolic blood pressure <100 mmHg
Where it is running
- University Hospital Zürich — Zurich, Canton of Zurich, Switzerland (enrolling)
Full record on ClinicalTrials.gov
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