Platelet-rich Plasma, Corticosteroid, or Lidocaine for Acromioclavicular Joint Pain

Stopped early · Phase 4

Conditions studied: Acromioclavicular Sprain

In brief

This study will compare three different treatment injections for the management of acromioclavicular joint dysfunction (ACJ Dysfunction). Patients that consent and enroll will be randomized to receive (1) a corticosteroid injection, (2) an injection of Platelet Rich Plasma, or (3) a Lidocaine injection. Follow-up will occur over a 1 year period.

Key facts

Study ID: NCT05161468
Run by: Brooke Army Medical Center
People needed: 34
Starts: 2021-08-12
Expected to finish: 2025-05-12
Last updated by the study team: 2025-05-14

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

TRICARE eligible beneficiaries (active duty, dependents, and military retired) with a primary complaint of AC joint pain.
Age 18-65 years
Able to speak and read English well enough to provide informed consent, follow study instructions and independently answer the questionnaires/surveys.
Tender to palpation over the AC joint that reproduces the specific pain they are seeking care for
Provocative test (cross-arm test, pain with push-ups, etc) that reproduces the specific pain they are here to seek care for

You may not qualify if…

In the last year, the subject received any invasive interventions including injections (corticosteroid, hyaluronic acid, lidocaine, PRP, etc.) or surgery for the affected shoulder - specifically to the AC joint.
Anyone separating from the military within 10 months (other than normal military retirement), pending a medical evaluation board, discharge from the military for medical reasons, or pending or undergoing any litigation for an injury
AC Joint separation that are with a severity of Grades III-VI (in most cases, these are treated surgically, although 78% of military surgeons recommended preferring conservative care for Grade III separations, and 86% recommending at least 3 months of conservative care before surgical consideration.
Systemic Disease that could otherwise be responsible for the shoulder pain (i.e. rheumatoid arthritis, gout, or psoriatic arthritis), non-musculoskeletal conditions causing shoulder pain, personal history of neoplasm, current or recent shoulder joint infection, acute fracture or dislocation of the shoulder related to the current episode of pain, or other more likely primary musculoskeletal shoulder disorders (rotator cuff pathology, bicipital tendonitis, etc.)
Concurrent adhesive capsulitis of the affected shoulder
History of intolerance or allergy to corticosteroids

Where it is running

Brooke Army Medical Center — San Antonio, Texas, United States
Madigan Army Medical Center — Tacoma, Washington, United States

Full record on ClinicalTrials.gov

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