Improving Continuous Renal Replacement Therapy Outcomes in Neonates and Infants Through Interdisciplinary Collaboration

Enrolling by invitation

Conditions studied: Acute Kidney Injury, Chronic Kidney Diseases, Renal Dialysis

In brief

To date, little knowledge exists related to the use of hemodialysis (HD) in infants and has been limited to mainly single center studies. The CARPEDIEM (CArdio-Renal PEdiatric Dialysis Emergency Machine) device, which can be used to provide hemodialysis in infants, has been launched in the United States. This study/registry is designed to obtain data on critically ill infants who require HD using the CARPEDIEM device to understand the indications for initiation, best practice in prescribing and performing treatment, expected treatment course, and outcomes of a dedicated infant continuous renal replacement therapy (CRRT) machine.

Key facts

Study ID

NCT05161078

Run by

Children's Hospital Medical Center, Cincinnati

People needed

1000

Starts

2021-12-16

Expected to finish

2031-12-31

Last updated by the study team

2026-03-23

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Treated with CARPEDIEM as part of standard of care at a participating institution within the United States

You may not qualify if…

• Parents/legally authorized representative unable or unwilling to provide consent

Where it is running

• Lucile Salter Packard Children's Hospital at Stanford — Palo Alto, California, United States
• Children's Hospital Colorado — Aurora, Colorado, United States
• Children's Hospital of Atlanta — Atlanta, Georgia, United States
• C.S. Mott Children's Hospital — Ann Arbor, Michigan, United States
• University of Nebraska Medical Center — Omaha, Nebraska, United States
• Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio, United States
• Texas Children's Hospital — Houston, Texas, United States
• Seattle Children's — Seattle, Washington, United States
• The Medical College of Wisconsin — Milwaukee, Wisconsin, United States

Full record on ClinicalTrials.gov

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