A Pilot Study of Total-body PET Using FDA-approved Radiotracers Beyond 18F-FDG
Enrolling by invitation
Conditions studied: Prostate Cancer, Breast Cancer, Neuroendocrine Tumors
In brief
The purpose of this research study is to test new ways to improve the usefulness of the world's first total-body positron emission tomography (PET)/computed tomography (CT) scanner (EXPLORER) by collecting data from PET scans using one of three different imaging agents: 18F-PSMA; 18F-FES; or, 68Ga DOTATATE. These imaging agents are approved by the FDA to be used for patients diagnosed with prostate cancer (18F-PSMA), neuroendocrine tumor (68Ga DOTATATE), or breast cancer (18F-FES).
Key facts
- Study ID
- NCT05160480
- Run by
- University of California, Davis
- People needed
- 9
- Starts
- 2024-06-07
- Expected to finish
- 2026-09-01
- Last updated by the study team
- 2026-03-10
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Persons >18 yo with suspected prostate cancer metastasis
- Prior imaging study (CT, and/or MRI and/or Bone scan and/or Fluciclovine scan) suspicious for metastatic disease, obtained within 4 months from the research scan date.
- 68Ga DOTATATE (n=3) or 64Cu-DOTATATE (n=3)
- Inclusion Criteria:
- Persons > 18 yo suspicious for or diagnosed with somatostatin receptor positive neuroendocrine tumors (NETs)
- Prior DOTATATE PET/CT scan suspicious for tumor obtained not earlier than 4 months from the research scan date.
You may not qualify if…
- Recent administration of long-acting somatostatin analogs
- Exclusion Criteria for all participants:
- Adults unable to consent
- Pregnant/lactating persons
- Prisoners
- Unable to lie supine for up to 90 minutes at different timepoints in the PET scanner
- Uncontrolled claustrophobia
- Any significant medical condition that in the opinion of the investigator would prevent the participant from participating and/or adhering to study related procedures or interfere with participant safety
Where it is running
- UC Davis EXPLORER Molecular Imaging Center — Sacramento, California, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.