Diagnostic Accuracy of M3 in Predicting Colorectal Advanced Adenoma Recurrence (M3-AA)
Recruiting now
Conditions studied: Colorectal Adenoma, Advanced Adenoma, Colorectal Polyp
In brief
The investigators aim to evaluate the diagnostic accuracy of FIT and the novel panel of four bacterial gene markers collectively named as M3, to detect recurrent advanced adenomas in patients with history of colonic adenomas.
Key facts
- Study ID
- NCT05144152
- Run by
- Chinese University of Hong Kong
- People needed
- 600
- Starts
- 2021-12-13
- Expected to finish
- 2025-06-15
- Last updated by the study team
- 2024-08-27
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Known colorectal adenomas during index colonoscopy;
- Available baseline M3 and FIT results before index colonoscopy;
- Aged ≥18 years old;
- Written informed consent obtained.
You may not qualify if…
- Refusal or unfit to undergo surveillance colonoscopy;
- Incomplete colonoscopy, incomplete removal of colorectal adenomas, or inadequate bowel preparation (defined as Boston Bowel Preparation Scale score 0 or 1 in any colonic segment) at index colonoscopy;
- Previous colonic resection;
- Personal history of colorectal cancer;
- Personal history of polyposis syndrome;
- Personal history of inflammatory bowel disease;
- Known pregnancy or lactation;
- Advanced comorbid conditions (defined as American Society of Anesthesiologists grade 4 or above);
Where it is running
- Prince of Wales Hospital — Shatin, New Territories, Hong Kong (enrolling)
Full record on ClinicalTrials.gov
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