The Influence of Beetroot Juice on Racial Disparities in Vascular Health
Completed · Not applicable · Has a placebo group
Conditions studied: Blood Pressure, Racial Disparities, Cardiovascular Risk Factor
In brief
Black adults are 30% more likely to die from cardiovascular disease (CVD) compared to White adults, and more than half of this racial disparity in cardiovascular mortality may be attributed to the substantially greater prevalence of high blood pressure and vascular dysfunction in Black adults. Nitric oxide (NO) is a potent signaling molecule and key regular of vascular function that is suspected to be reduced in black individuals, but can be enriched by dietary nitrate (e.g., arugula, spinach, beets). The purpose of this study is to test the hypothesis that increasing NO bioavailability via nitrate-rich beetroot juice (BRJ) will lower blood pressure and improve vascular health in Black adults.
Key facts
- Study ID
- NCT05132556
- Run by
- Georgia Southern University
- People needed
- 40
- Starts
- 2021-11-01
- Expected to finish
- 2023-10-04
- Last updated by the study team
- 2023-10-05
Who can join
Age: 18 and older, up to 39. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Between 18-39 years of age
- Body mass index (BMI) below 30 kg/m\^2
- Free from signs or symptoms of neurologic, cardiovascular (e.g., heart attack, stroke, heart failure, arrhythmia), metabolic, and/or renal disease
- Have a blood pressure no lower than 90/50 mmHg
- Are not currently smoking, using smokeless tobacco, nor smoked within the past 12 months
You may not qualify if…
- Low blood pressure - less than 90/50 mmHg
- History of cardiovascular disease
- History of cancer
- History of diabetes
- History of kidney disease
- Obesity (BMI > 30 kg/m\^2)
- Smoking or tobacco use
- Current pregnancy
- Nursing mothers
- Communication barriers
Where it is running
- Biodynamics and Human Performance Center — Savannah, Georgia, United States
Full record on ClinicalTrials.gov
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