Immunophenotyping in Patients With Osteoporosis

Recruiting now

Conditions studied: Immunophenotyping Blood Samples of Patients With Osteoporosis

In brief

In addition to a medical history and clinical examination, the diagnosis of osteoporosis includes the measurement of bone surface density by means of dual X-ray absorptiometry (DXA). In addition, blood tests are performed for certain parameters, such as vitamin D, calcium, phosphate and C-reactive protein. In order to optimize osteoporosis diagnostics, the development of further specific methods is required. The modulation of the immune system seems promising in this respect, since osteoporosis is based on an inflammatory reaction. Various regulatory markers of the innate and acquired immune system, which seem to be relevant in the development of the disease, have already been detected in osteoporosis patients. This study may help to gain new insights into disease-associated immunoregulatory markers that could revolutionize both the diagnosis and therapy of osteoporosis in the long term. By means of a simple blood test, patients could be diagnosed early and without additional radiation exposure, and effective therapy options could be developed.

Key facts

Study ID

NCT05132348

Run by

University Hospital, Bonn

People needed

250

Starts

2021-10-10

Expected to finish

2026-10-19

Last updated by the study team

2021-11-24

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients (≥ 18 years) diagnosed with osteoporosis.
• Written informed consent from the patient

You may not qualify if…

• Patients without diagnosed osteoporosis
• Patients without written informed consent
• Patients < 18 years old
• Patients with secondary osteoporosis

Where it is running

• University Hospital of Bonn — Bonn, Northrhine Westfalia, Germany (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.