Proning Early in Awake COVID-19 Hypoxic Respiratory Failure (PREACHR) Study

Completed · Not applicable

Conditions studied: Covid19, Respiratory Failure

In brief

The aim of this proposal is to study whether proning, a technique that has previously been shown to improve lung function in patients with acute respiratory distress syndrome (ARDS), can prevent those with mild to moderate symptoms of COVID-19 from progressing to severe disease when initiated early, thereby averting intubation, reducing hospitalization, and, ultimately, decreasing mortality.

Key facts

Study ID

NCT05130541

Run by

New York Hospital Queens

People needed

219

Starts

2020-06-01

Expected to finish

2021-05-01

Last updated by the study team

2021-11-23

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age >18
• Presenting to the ED with symptoms suggestive of COVID-19
• Assessed by ED attending physician to not require emergent intubation
• Normal mental status and ability to communicate symptoms/distress
• Able to follow instructions independently

You may not qualify if…

• Severe respiratory distress requiring immediate intervention
• Unable to follow verbal instructions
• Unable to communicate their needs, symptoms, or distress
• Inability to tolerate prone positioning due to mental status or habitus

Where it is running

• New York Presbyterian Queens — Flushing, New York, United States

Full record on ClinicalTrials.gov

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