Embolization of the Splenic Artery After Trauma

Completed · Not applicable

Conditions studied: High-grade Splenic Injuries

In brief

Our aim is to conduct a multi-center, Bayesian, randomized clinical trial to evaluate the primary technical success of coils and vascular plugs for proximal splenic artery embolization in the setting of high-grade splenic trauma. The investigator has previously demonstrated the feasibility of such a study in a single center pilot trial.

Key facts

Study ID

NCT05128955

Run by

Andrew J. Gunn

People needed

180

Starts

2022-05-10

Expected to finish

2026-04-22

Last updated by the study team

2026-06-29

Who can join

Age: 15 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• ≥15 years of age
• Trauma resulting in grade III or higher splenic injury on contrast-enhanced CT
• Splenic injury to be treated by non-operative management as decided by attending trauma surgeon and interventional radiologist
• The attending interventional radiologist determines that the patient will undergo proximal splenic artery embolization with the specific method to be decided by randomization.

You may not qualify if…

• Inability to obtain informed consent
• ≤ 50kg
• Uncorrectable coagulopathy
• Patient is immunocompromised
• Pregnant
• Breast-feeding
• Non-English speakers
• Prisoners

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States
• Wake Forest Baptist Medical Center — Winston-Salem, North Carolina, United States
• Ohio State University Medical Center — Columbus, Ohio, United States
• Prisma Health — Greenville, South Carolina, United States
• The University of Texas Health Science Center at Houston McGovern Medical School — Houston, Texas, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.