Can Overall Adenoma Detection Rate Replace Screening Adenoma Detection Rate ? Multicenter Study

Recruiting now

Conditions studied: Adenoma Detection Rate, Colonoscopy

In brief

This is a prospective equivalence colonoscopy study evaluating whether overall adenoma detection rate (ADR) is a reliable alternate for screening ADR. Overall indication includes screening, surveillance, and diagnostic indications.

Key facts

Study ID

NCT05125939

Run by

Evergreen General Hospital, Taiwan

People needed

2700

Starts

2021-11-20

Expected to finish

2026-09-30

Last updated by the study team

2025-08-07

Who can join

Age: 50 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• consecutive patients aged ≥50 years undergoing colonoscopy are eligible for enrollment.

You may not qualify if…

• high risk family history of colorectal cancer (CRC) e.g., familial adenomatous polyposis, hereditary non-polyposis CRC syndrome, multiple first degree relatives with CRC, or a single first degree relative with CRC at <60 years
• serrated polyposis syndrome
• inflammatory bowel disease
• colonoscopy to remove a large neoplastic polyps
• obstructive lesions of the colon
• gastrointestinal bleeding
• current participation in other studies
• hospitalized patients
• mental retardation
• pregnancy
• refusal to provide a written informed consent.

Where it is running

• Evergreen General Hospital — Taoyuan, Taiwan (enrolling)
• Sepulveda Ambulatory Care Center, VAGLAHS — North Hills, California, United States
• E-Da Dachang Hospital — Kaohsiung City, Taiwan
• E-Da Hospital — Kaohsiung City, Taiwan
• Keelung Chang Gung Memorial Hospital — Keelung, Taiwan
• Linkou Chang Gung Memorial Hospital — Taoyuan, Taiwan

Full record on ClinicalTrials.gov

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