Pathophysiologic Mechanism for Arrhythmias and Impaired Aerobic Capacity in Tetralogy of Fallot and Other Congenital Heart Diseases

Recruiting now

Conditions studied: Tetralogy of Fallot, Congenital Heart Disease

In brief

This study is being done to determine the mechanism(s) contributing to the onset of symptoms (i.e. shortness of breath and/or palpitations) as well as changes in heart structure in patients with congenital heart disease (CHD)

Key facts

Study ID

NCT05122962

Run by

Mayo Clinic

People needed

300

Starts

2021-11-01

Expected to finish

2026-10-01

Last updated by the study team

2026-02-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Moderate (or greater) PR based on quantitative Doppler echocardiography.
• Repaired TOF
• Congenital Heart Disease diagnosis including but not limited to Ebstein's anomaly, coarctation of the aorta (COA), Fontan palliation, transposition of the great arteries, congenitally corrected transposition of the great arteries.

You may not qualify if…

• Pregnant Women
• Unable to undergo CMRI

Where it is running

• Mayo Clinic in Rochester — Rochester, Minnesota, United States (enrolling)

Full record on ClinicalTrials.gov

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