Effects of Analgesia Nociception Index (ANI)-Guided Analgesia on Postoperative Bowel Function.

Recruiting now · Not applicable

Conditions studied: Postoperative Bowel Function Recovery

In brief

Investigators will examaine the effects of Analgesia Nociception Index (ANI)-guided analgesia on postoperative bowel function recovery in laparoscopic colorectal surgery. This is a prospective randomized-controlled study. Investigators will randomly divide the patients into two groups. In ANI group, remifentanil infusion rate during anesthesia will be adjusted according to ANI monitoring. In Control group, remifentanil infusion rate during anesthesia will be adjusted according to the conventional method of blood pressure and heart rate monitroing. And Investigators will evalualte the bowel function recovery in both groups after surgery, and compare between the two groups.

Key facts

Study ID

NCT05122078

Run by

Gangnam Severance Hospital

People needed

80

Starts

2021-11-29

Expected to finish

2025-10-14

Last updated by the study team

2024-09-05

Who can join

Age: 19 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients over 19 years who undergo laparoscopic colorectal surgery for colorectal cancer at Gangnam Severance Hospital, Seoul, South Korea.

You may not qualify if…

• Emergency surgery
• Patients with history of open abdominal surgery
• Patients with arrhythmia
• Patients with pacemaker insertion
• Patients with history of heart transplantation
• Patients taking medications that may affect ANI (antimuscarinics, alpha-agonists, beta blockers)
• Patients with chronic opioid medication.
• Cognitive impairment
• Unable to read consent form (eg illiterate, foreigner, etc.)

Where it is running

• GangnamSeverance Hospital — Seoul, South Korea (enrolling)

Full record on ClinicalTrials.gov

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