Video Telehealth Pulmonary Rehabilitation to Reduce Hospital Readmission in Chronic Obstructive Pulmonary Disease
Running, not enrolling · Not applicable
Conditions studied: Chronic Obstructive Pulmonary Disease
In brief
The purpose of this study is to compare the efficacy and safety of a real time video telehealth pulmonary rehabilitation intervention with standard of care in patients hospitalized for an exacerbation of chronic obstructive pulmonary disease (COPD) to determine the impact on hospital readmissions and respiratory morbidity, and to investigate the cost-effectiveness of the intervention.
Key facts
- Study ID
- NCT05119556
- Run by
- University of Alabama at Birmingham
- People needed
- 301
- Starts
- 2022-06-28
- Expected to finish
- 2028-02-27
- Last updated by the study team
- 2026-04-13
Who can join
Age: 40 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age 40 or greater
- Clinical diagnosis of COPD
- Hospitalized for acute exacerbation of COPD.
- Be willing to adhere to trial and follow-up procedures and give informed consent
You may not qualify if…
- Secondary diagnosis of congestive heart failure that is severe as documented by active symptoms, New York Heart Association (NYHA) functional classification IV or left ventricular ejection fraction <25% on echocardiography
- Other respiratory conditions that could confound the diagnosis such as asthma, pulmonary fibrosis, bronchiectasis, and lung cancer. Participants with pneumonic exacerbations of COPD will be included.
- Primary diagnosis of COVID pneumonia. Individuals with incidentally detected COVID or persistently positive for COVID but deemed to be convalescent will not be excluded.
- Active cancers on chemotherapy or radiation therapy
- Immunosuppressed states predisposing to frequent hospitalizations including uncontrolled HIV/AIDS
- Active or recent (within 1 month) myocardial infarction
- Angina not well-controlled by medication
- Unstable cardiac arrhythmias, atrial or ventricular
- Supplemental oxygen requirement greater than 5 liters per minute at either rest or with exertion
- Significant cognitive dysfunction, including dementia, that in opinion of investigator would impair ability to safely or effectively engage in study protocol
- Participants with any terminal medical illnesses as diagnosed by a physician, and/or on hospice
- Currently enrolled in and participating in pulmonary rehabilitation
- Treatment with chronic or newly initiated home ventilatory support. Those on in-patient short-term non-invasive ventilation will not be excluded.
- Special patient groups such as prisoners and institutionalized patients
- Participants with musculoskeletal comorbidities or physical infirmities that preclude participation in an exercise program
- Current participation in any other interventional clinical trial
- Inability to understand and speak English during exercise sessions
- Inability or unwillingness to comply with study and/or follow-up procedures outlined in the protocol
Where it is running
- University of Alabama at Birmingham — Birmingham, Alabama, United States
- Northwestern Memorial Hospital — Chicago, Illinois, United States
- University of Iowa — Iowa City, Iowa, United States
- Johns Hopkins University — Baltimore, Maryland, United States
- University of Maryland — College Park, Maryland, United States
- Boston VA Hospital — Boston, Massachusetts, United States
- HealthPartners Institute — Bloomington, Minnesota, United States
- Minnesota VA HealthCare System — Minneapolis, Minnesota, United States
- Northern Westchester Hospital/Northwell Health — Chappaqua, New York, United States
- Wake Forest University — Winston-Salem, North Carolina, United States
- Cincinnati VA Hospital — Cincinnati, Ohio, United States
- Cleveland Clinic — Cleveland, Ohio, United States
- Temple University Hospital — Philadelphia, Pennsylvania, United States
- University of Pittsburgh — Pittsburgh, Pennsylvania, United States
- Baylor College of Medicine — Houston, Texas, United States
Full record on ClinicalTrials.gov
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