Diagnosing Deep-vein Thrombosis Early in Critically Ill Patients
Recruiting now · Not applicable
Conditions studied: Deep Vein Thrombosis, Pulmonary Embolism
In brief
The DETECT randomized controlled trial addresses the question of whether surveillance ultrasound in critically ill patients by facilitating DVT detection reduces the incidence of PE and lowers all-cause 90-day mortality. The primary outcome is 90-day all-cause mortality.
Key facts
- Study ID
- NCT05112705
- Run by
- King Abdullah International Medical Research Center
- People needed
- 1800
- Starts
- 2023-03-21
- Expected to finish
- 2026-12-01
- Last updated by the study team
- 2025-09-19
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Medical, surgical or trauma ICU patients ≥18 years old.
- Patients who are expected to stay in the ICU more than 2 calendar days (unlikely to be discharged out of ICU on the day of admission or on the next day).
You may not qualify if…
- Patients with DVT or PE diagnosed within the last year.
- Patients receiving chronic systemic anticoagulation.
- Patients who have received up to the time of ICU admission or are receiving therapeutic doses of anticoagulation with UFH, LMWH, or other anticoagulants.
- Inability or contraindication to obtain adequate ultrasound on the lower extremities (Burns in the lower extremities, lacerations, active skin infection, \& ischemic limb in the legs, large dressings in the thighs that prevent adequate ultrasounds OR amputated foot or leg on one or two sides)
- Patients with Inferior Vena Cava (IVC) Filter.
- Known or suspected pregnancy.
- Limitation of life support, life expectancy <7 days or palliative care.
- Previously enrolled in DETECT trial within the last 180 days.
- Enrolled in another trial for which co-enrolment is not approved.
Where it is running
- King Abdulaziz Medical City — Riyadh, Riyadh Region, Saudi Arabia (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.