A Study to Evaluate White Matter Hyperintensities in Migraine
Running, not enrolling · Not applicable
Conditions studied: Migraine, Small Vessel Ischemic Disease, Multiple Sclerosis
In brief
The purpose of this research is to better understand brain white matter hyperintensities (WMH) in women with migraines
Key facts
- Study ID
- NCT05112289
- Run by
- Mayo Clinic
- People needed
- 50
- Starts
- 2021-08-16
- Expected to finish
- 2026-08-01
- Last updated by the study team
- 2025-09-05
Who can join
Age: 20 and older, up to 59. Sex: female. Healthy volunteers: not accepted.
You may not qualify if…
- History of SVI and/or history of MS or other neurological disease other than migraine.
- History of cancer or organ transplantation.
- Contraindication to MRI.
- Pregnancy.
- History of abnormal brain MRI other than WMH.
- Subjects not willing to comply with the study procedures will be removed from the study.
- Inclusion Criteria - SVI disease (n=10):
- Female only
- Ages > 60 years.
- Presence of WMH on MRI.
- Exclusion Criteria:
- History of migraine and/or history of MS or other neurological disease other than SVI.
- History of cancer or organ transplantation.
- History of abnormal brain MRI other than WMH.
- Pregnancy.
- History of abnormal brain MRI other than WMH.
- Subjects not willing to comply with the study procedures will be removed from the study.
- Inclusion Criteria - MS (n=10):
- Female only.
- Ages 20-45.
- Presence of WMH on MRI.
- Exclusion Criteria:
- History of migraine and/or history of SVI or other neurological disease other than MS.
- History of cancer or organ transplantation.
- History of abnormal brain MRI other than WMH.
Where it is running
- Mayo Clinic in Arizona — Phoenix, Arizona, United States
Full record on ClinicalTrials.gov
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