Real-world Evaluation of Brolucizumab for the Treatment of Neovascular (Wet) Age-related Macular Degeneration (AMD) (Komodo Health)

Completed

Conditions studied: Age-related Macular Degeneration (AMD)

In brief

This study was a retrospective cohort study of patients to assess the early insights into real-world safety among wet AMD patients initiating brolucizumab. Evidence was generated to describe their patient characteristics and clinical outcomes. The study was conducted using the Komodo Healthcare Map.

Key facts

Study ID

NCT05111743

Run by

Novartis Pharmaceuticals

People needed

9261

Starts

2020-06-17

Expected to finish

2020-12-18

Last updated by the study team

2021-12-21

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• ≥1 Healthcare Common Procedure Coding System (HCPCS) code (J code) or National Drug Code (NDC) for treatment with brolucizumab during the index period (date of earliest code = index date)
• ≥18 years old on the index date
• ≥1 International Classification of Diseases, Clinical Modification-9/10 (ICD-9/10) code for wet AMD in the 36 months prior to or on the index date
• Note: Off-label use of brolucizumab is not expected given payer access restrictions in the US
• ≥24 months of continuous enrollment prior to the index date
• ≥1 follow-up visit related to their wet AMD after the index date

You may not qualify if…

• Use of brolucizumab prior to 08-Oct-2019 (e.g. clinical trials)
• Unknown laterality of the index eye on the index date
• Patients with no data throughout the 12 months immediately prior to the index date

Where it is running

• Novartis Investigative Site — East Hanover, New Jersey, United States

Full record on ClinicalTrials.gov

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