Developing a Clinical Outcome Assessment for Opioid Craving
Completed · Not applicable
Conditions studied: Opioid Craving, Opioid Use Disorder, Measure Development
In brief
The purpose of this study is to collect information about opioid craving so that the investigators can develop an opioid craving assessment to improve treatments for individuals with opioid use disorder. To collect this information, the investigators are recruiting individuals in treatment for opioid use disorder who will complete cue-induced opioid craving tasks where these individuals will: (1) look at pictures of neutral objects and touch neutral objects (e.g., water bottles or flashlights), (2) look at opioid-related images, and (3) look and touch opioid-related objects. Participants will then complete a one-on-one interview about the thoughts, feelings and physical sensations the participants experienced during the cue-induced craving session. Participants will also complete questionnaires and existing opioid craving assessments. Finally, participants will provide formal feedback about existing opioid craving assessments with cognitive interviews.
Key facts
- Study ID
- NCT05109429
- Run by
- University of Maryland, Baltimore
- People needed
- 74
- Starts
- 2022-03-03
- Expected to finish
- 2026-07-16
- Last updated by the study team
- 2026-07-27
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- 18 years of age and older
- Opioid-positive urine sample at admission visit (excluding individuals receiving Naltrexone).
- Current opioid use disorder per Diagnostic Statistical Manual (DSM)-5
- Currently in treatment for opioid use disorder
You may not qualify if…
- Being pregnant or breastfeeding, or may become pregnant during the trial
- History of psychosis or mania or other serious psychiatric disorders assessed by the Mini International Neuropsychiatric Interview
- Past 30-day suicidal behavior assessed by the Columbia Suicide Severity Rating Scale
- Have circumstances that would interfere with study participation (e.g., impending jail).
- Positive for illicit substances except opioids and cannabis
- Current substance use disorder other than opioid or nicotine
- Current intoxication
Where it is running
- Behavioral Pharmacology Research Unit — Baltimore, Maryland, United States
Full record on ClinicalTrials.gov
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