Imaging Measures of Respiratory Health Registry
Recruiting now
Conditions studied: Respiratory Disease, Healthy
In brief
This is a prospective, observational cohort registry that aims to collect data on pulmonary structure and function in healthy people and those with respiratory disease, using structural and functional pulmonary 1H-MRI and hyperpolarized 129Xe-MRI. Outcome measures generated from MRI may include but are not limited to measures of regional ventilation, pulmonary microarchitecture, and regional gas exchange. Additionally, one of the goals of the registry is to facilitate the development of novel image analysis techniques that have not yet been invented. These data will be stored along with demographic data, clinical data, and pulmonary function testing (PFT) data. This is an open registry. Eligible local and international investigators/institutions can apply for access.
Key facts
- Study ID
- NCT05102825
- Run by
- University of British Columbia
- People needed
- 1000
- Starts
- 2020-06-11
- Expected to finish
- 2045-06-01
- Last updated by the study team
- 2021-11-02
Who can join
Age: any, up to 99. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Physician-diagnosed lung disease - based on a diagnosis made by a treating staff physician and confirmed by the principal investigator.
- Age 0-99 years.
- Informed consent by participant, parent, or legal guardian
- In the opinion of the Investigator, the participant will likely be able to perform maneuvers to obtain technically acceptable pulmonary XeMRI images.
You may not qualify if…
- Physical findings at screening that, in the opinion of the Investigator, would compromise the safety of the participant or the quality of the research data.
- Requirement of supplementary oxygen to maintain an oxygen saturation above 95%.
- Failed MRI screening form.
- History of claustrophobia.
- Known current pregnancy or lactation.
- Healthy
- Inclusion Criteria:
- Age 0-99 years
- Informed consent by participant, parent, or legal guardian
- In the opinion of the Investigator, the participant will likely be able to perform maneuvers to obtain technically acceptable pulmonary MRI images.
- Exclusion Criteria
- Physician-diagnosed lung disease.
- Failed MRI screening form.
- History of claustrophobia.
- Physical findings at screening that, in the opinion of the Investigator, would compromise the safety of the participant or the quality of the research data.
- Known current pregnancy or lactation.
Where it is running
- British Columbia Children's Hospital — Vancouver, British Columbia, Canada (enrolling)
- St. Paul's Hospital — Vancouver, British Columbia, Canada (enrolling)
Full record on ClinicalTrials.gov
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